Webb17 sep. 2024 · Bacterially-expressed and purified Trx-His-Pib2 (304-635) and TORC1 purified from yeast on magnetic beads were incubated with the indicated amino acids … WebbOur data, therefore, extend the function of Pib2 to a hub that integrates both glucose and, as reported earlier, glutamine signals to control TORC1. We further demonstrate that Snf1 phosphorylates the TORC1 effector kinase Sch9 within its N-terminal region and thereby antagonizes the phosphorylation of a C-terminal TORC1-target residue within Sch9 itself …
The yeast H+-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 …
Webb9 okt. 2024 · Pib2 reflects its domain structure (see Section5for details). In mammals, amino acid and growth factor signals to mTORC1 are mediated by the Rag-Ragulator … WebbUniProt P53191 · PIB2_YEAST Protein Glutamine sensor PIB2 Gene PIB2 Status UniProtKB reviewed (Swiss-Prot) Organism Saccharomyces cerevisiae (strain ATCC 204508 / … check my kindle fire for virus
PIB2 SGD
WebbPib2 as an Emerging Master Regulator of Yeast TORC1 Article Full-text available Oct 2024 Riko Hatakeyama Cell growth is dynamically regulated in response to external cues such as nutrient... In Saccharomyces cerevisiae, Pib2 has been shown to be involved in regulating TORC1 signaling. Pib2 is found at the yeast vacuole and endosomes. The PI3P binding FYVE domain of Pib2 is key for this localization. Pib2 also interacts with some TORC1 components, including Kog1 and Tor1, and has been shown to be necessary for TORC1 reactivation following inhibition by rapamycin or nutrient starvation. Additionally, Pib2 is essential for TORC1 reactivation by stimulation with leuci… WebbPIB2 S000007475, YGL023C Protein of unknown function; contains FYVE domain; similar to Fab1 and Vps27 GO Process(0) GO Function(0) GO Component(1) Gene Ontology … check my kroger fuel points online