Growth arrest specific 6

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August undefined, 2024

WebJan 12, 2024 · Growth arrest-specific 6 (GAS6) is a vitamin K-dependent protein related to inflammation, fibrosis, as well as platelet function. Genetic ablation of GAS6 in mice protects against cardiac hypertrophy and dysfunction. Nonetheless, the association between plasma GAS6 levels and acute heart failure (AHF) patients is still unknown. We measured … WebGAS6 INFORMATION. Proteini. Full gene name according to HGNC. Growth arrest specific 6. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. GAS6 (AXLLG, AXSF, DKFZp666G247, FLJ34709) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).

Targeting GAS6 in cancer, fibrosis and viral infection - Drug …

WebMar 4, 2015 · Growth Arrest-Specific 6 (GAS6) is a vitamin K-dependent protein (VKDP) which is expressed by diverse tissues such as endothelial cells, smooth muscle cells, … WebMar 29, 2024 · Growth Arrest-Specific 6 in Chromophobe Renal Cell Carcinoma. Mikuteit M, Zschäbitz S, Erlmeier M, Autenrieth M, Weichert W, Hartmann A, Steffens S, Erlmeier … cedarhurst assisted living missouri

Growth arrest-specific gene 6 (GAS6). An outline of its …

WebAn Overview for Parents: Growth arrest can occur as a result of trauma, metabolic disorders, malnutrition and underlying skeletal dysplasias. Any disruption or injury to the … WebApr 10, 2024 · Background Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM’s molecular mechanisms constitutes an obstacle to developing effective therapy. In this study, we examined key regulators mediating UM progression and their clinical relevance. … WebSep 27, 2024 · GAS6 (growth arrest specific 6) exposure promotes the formation of monocyte derived Axl+ Siglec-6+ dendritic cells (AS DCs).A, Human CD14 + monocytes … buttery leather boots

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14456 - Gene ResultGas6 growth arrest specific 6 [ (house mouse)]

WebIn this review, we summarize three important emerging VKDPs: Growth arrest‑specific protein 6 (Gas 6), Gla‑rich protein (GRP) and periostin in terms of their functions in physiological and pathological conditions. As examples, carboxylated Gas 6 and GRP effectively protect blood vessels from calcification, Gas 6 protects from acute kidney ... WebConversely, under chronic stress, increased levels of corticosterone prolong HFSC quiescence and maintain hair follicles in an extended resting phase. Mechanistically, … buttery leather handbags dillardsWebGas6 (growth arrest-specific gene 6) is the last addition to the family of plasma vitamin K-dependent proteins. Gas6 was cloned and characterized in 1993 and found to be similar to the plasma anticoagulant protein S. cedarhurst assisted living naperville il

"WebPlasma protein growth arrest-specific 6 (GAS6) and matrix Gla protein (MGP) are crucial mediators of vascular calcification and are involved in the development of vascular … " - Growth arrest specific 6

Growth arrest specific 6

Gas6 expression is reduced in advanced breast cancers

WebNov 16, 2024 · Growth arrest-specific gene 6 protein (Gas6) is avitamin K-dependent tissue bound protein. Gas6 has been shown to promote growth and therapy resistance among different types of cancer as well as thromboembolism. The aim of this prospective screening study: ClinicalTrials.gov; Identifier: NTC3782025, was to evaluate the effects … http://www.informatics.jax.org/marker/MGI:95660

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Webアズワンの【AXEL】84-4418-23 GAS6 (Growth Arrest Specific Protein 6, AXLLG, AXSF, AXL Stimulatory Factor, AXL receptor tyrosine kinase ligand) 200ul 363225のコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い分野に750万点以上の品揃えでお応えする商品サイト。3000円以上ご注文で送料無料。 WebGrowth arrest-specific gene 6 (Gas6) belongs to the family of vitamin K-dependent coagulation proteins, but in contrast to its other members, has only a limited role in hemostasis. Instead, Gas6 plays a prominent role in conditions of injury, inflammation and repair. Gas6 amplifies the activation of various cell types including endothelial ...

WebApr 15, 2024 · Mechanistically, corticosterone acts on the dermal papillae to suppress the expression of Gas6, a gene that encodes the secreted factor growth arrest specific 6. Restoring Gas6 expression... WebDec 2, 2024 · In cancer models and human specimens, specific microenvironmental cues such as transforming growth factor–β2 (TGF-β2) ( 6 ), retinoic acid ( 7 ), bone morphogenetic protein 7 (BMP7), periostin, leukemia inhibitory factor, and growth arrest specific 6 (GAS6) can activate transcriptional programs of quiescence, pluripotency, and …

WebMar 9, 2024 · The growth-arrest specific 6 (GAS6) protein has emerged in recent years as an attractive target for drug development primarily because it is the sole ligand for the AXL receptor tyrosine kinase, which plays critical roles in cancer, fibrosis, and viral infection. WebHere, we tested the hypothesis that expression of growth arrest–specific 6 (GAS6), the ligand of receptor tyrosine kinase AXL, is associated with chemotherapy response and that sequestration of GAS6 with AVB-S6–500 (AVB-500) could improve tumor response to chemotherapy and PARP inhibitors.

WebNov 16, 2015 · What Is New? Growth arrest–specific 6 (GAS6) is upregulated in failing human hearts, pressure overload–induced murine hypertrophic... For the first time, …

WebApr 4, 2024 · Gas6 growth arrest specific 6 [ (house mouse)] Gene ID: 14456, updated on 22-Jan-2024. Summary. Enables receptor ligand activity. Acts upstream of or within … buttery kettle popcornWebJan 3, 2024 · We revealed that growth arrest specific 6 (GAS6), a ligand of the TYRO3–AXL–MERTK signaling system, plays a critical role in this process. Upon birth, microorganisms residing in the oral cavity induce expression of GAS6 in oral tissues; GAS6 in turn regulates antibacterial function in these tissues. buttery leather couchWebAim: Gas6 is known to be elevated in sepsis, correlating with the severity of infection and organ failure. We aimed to investigate the performance of Gas6 plasma levels at … cedarhurst assisted living sparta ilWebGrowth arrest-specific 6 (Gas6) encodes the Gas6 protein that binds to TAM receptors (Tyro3, Axl, Mer), resulting in PI3K and Akt pathway activation. 224,225 In platelets, this Gas6 plays a critical role in outside-in signaling, as … buttery leather flatsWebpointed to a secreted protein called growth arrest-specific 6 (GAS6) as a candidate molec - ular messenger. Indeed, delivering GAS6 into the skin using an adenovirus vector (a com-mon tool in gene therapy) not only stimulated hair growth in normal mice, but also restored hair growth during chronic stress or cortico-sterone feeding. buttery kimchi chicken buttery kimchi shrimp recipeWebJun 7, 2004 · Growth arrest-specific protein 6. Short names. GAS-6. Alternative names. AXL receptor tyrosine kinase ligand; Gene names. Name. Gas6. Organism names. … buttery leather brown boots women