Gli2 molecular weight

Author: zcdy

August undefined, 2024

WebOct 11, 2024 · GLI2 binds to the ARHGEF16 promoter and activates gene transcription. Glioma cells U87 and U118 overexpressing ARHGEF16 showed enhanced migration and proliferation relative to the control cells, while knockdown of ARHGEF16 in H4 cells led to decreased cell proliferation compared to the control H4 cells. WebCompare GLI2 (NM_005270) Human Tagged ORF Clone from OriGene Technologies on Biocompare.com ... Target GLI2; Molecular Weight 4758 bp; Selectable Marker Kanamycin (25 ug/mL) Conjugate/Tag/Label ... Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation Molecular and Cellular …

GLI2 protein expression summary - The Human Protein Atlas

WebMar 21, 2024 · Molecular mass: 167783 Da Protein existence level: PE1 Quaternary structure: Interaction with ZIC1 and ZIC2 (By similarity). Interacts with STK36 … WebGLI2 GLI family zinc finger 2 [ (human)] Gene ID: 2736, updated on 21-Mar-2024 Summary This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. magna international lancaster ohio

GLI Genes and Their Targets in Epidermal Development …

WebMar 21, 2024 · Gli2 is necessary for normal endochondral bone development. Processing and degradation of Gli2 are suppressed by Shh signaling in vivo; this is the first … WebGLI2 gene is localized on chromosome 2q14. GLI2 deficiency phenotype follows an autosomal dominant inheritance pattern. Four heterozygous mutations (c.2274del1, … WebJan 2, 2024 · Here, using whole-exome, targeted capture and RNA-sequencing, we report recurrent FHL2-GLI2 fusion genes in 65% (17/26) of SSTs and other GLI2 rearrangements in additional 15% (4/26) SSTs, none of which are detected in other types of SCSTs (n = 48) or common cancer types (n = 9,950). magna international llc

GLI2 Polyclonal Antibody (PA1-28838) - Thermo …

Gli2 GLI-Kruppel family member GLI2 [ (house mouse)]

WebGLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3 (3). These GLI proteins are similar to the Drosophila homolog Cubitus interruptus (Ci) and function … WebGLI2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. magna international inc headquartersWebGli2 is mostly regarded as a transcriptional activator, even though it is also suggested to have a weak repressing activity. What the molecular basis for its possible dual function … magna international liverpool

"WebGLI2 Antibody (PA1-28838) in IHC (P) Immunohistochemistry analysis of GLI2 was performed in several formalin-fixed and paraffin embedded mouse testis using GLI2 Polyclonal Antibody ( Product # PA1-28838) at 10 … " - Gli2 molecular weight

Gli2 molecular weight

WebZinc finger protein GLI2. GLI2 THP . 1,586: Annotation score: A0A7I2PJA1: A0A7I2PJA1_HUMAN: Zinc finger protein GLI2. GLI2 ... Main funding by: National Institutes of Health The European Molecular Biology Laboratory State Secretariat for Education, Research and Innovation SERI. WebGLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3 (3). These GLI proteins …

Did you know?

WebA synthetic peptide corresponding to internal region of mouse Gli2. (PAB10270) - Products - Abnova. ... Molecular weight markers are shown (M) using the 700 nm channel (red). IRDye® 800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. WebGLI2; GLI family zinc finger 2: Aliases: CJS, HPE9, PHS2, THP1, THP2 : Location: 2q14.2: Summary: ... Furthermore, we identified Atoh1 as a target and molecular accomplice of …

WebFeb 28, 2024 · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In … WebOct 14, 2024 · 2. BET Proteins’ Function. The bromodomain and extraterminal domain (BET) family belongs to BRD proteins and comprises four evolutionarily conserved members, including ubiquitously expressed BRD2, BRD3 and BRD4 and a testis-specific BRDT [3,4].The BET family is characterised by the presence of two N-terminal …

WebGLI2 Full Name Zinc finger protein GLI2 Weight 167.783kDa Superfamily GLI C2H2-type zinc-finger protein family Alternative Names WebDec 17, 2024 · GLI2 belongs to the GLI family, ... A pdb file containing the structural coordinates was downloaded and visualized using PyMOL molecular graphics system v.2.2. The five Zn-fingers are colored blue, with amino acids containing variants found in patients visualized as red sticks. ... He was born at 37 weeks of gestation with a birth …

WebNov 25, 2008 · HGNC:4318 GLI2 MIM 165230 gene 610829 phenotype 615849 phenotype VEuPathDB HostDB:ENSG00000074047 neXtProt NX_P10070 Subcellular Location UniProt Annotation GO Annotation Nucleus 1 publication Cytoplasm By similarity Cell projection, cilium By similarity Note: STK36 promotes translocation to the nucleus.

WebGLI2 INFORMATION. Proteini. Full gene name according to HGNC. GLI family zinc finger 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, … magna international inc. mgaWebDec 5, 2024 · GLI-2 Antibody (C-10) is a mouse monoclonal IgG 1 κ GLI-2 antibody, cited in 47 publications, provided at 200 µg/ml raised against amino acids 841-1140 mapping near the C-terminus of GLI-2 of human … magna international logisticsWebMar 21, 2024 · Size: 1586 amino acids Molecular mass: 167783 Da Protein existence level: PE1 Quaternary structure: Interaction with ZIC1 and ZIC2 (By similarity). Interacts with STK36 (PubMed:10806483). Interacts with SUFU; this inhibits transcriptional activation mediated by GLI2 (PubMed:24311597). Interacts (via C-terminal internal region) with … magna international inc class aWebMar 23, 2006 · The complete ORF of human GLI2 starts from exon 2 and terminates in exon 14 predicting a protein of 1569 aa with molecular weight of 166 kD (Fig. 4 ). The predicted protein structure differs from that described by Roessler et al. [ 33] by a17 aa sequence (GQVSGHGSCGCALPLSQ). cpia albanohttp://www.cancerindex.org/geneweb/GLI2.htm cpia albamondoviWebSep 18, 2024 · We report for the first time that GLI1 and GLI2 physically and functionally interact in cancer cells. GLI1 and GLI2 were shown to co-immunoprecipitate in PANC1 pancreatic cancer cells and RMS13 rhabdomyosarcoma cells. Mapping analysis demonstrated that the zinc finger domains of both proteins are required for their … cpia acqui termeWebView mouse Gli2 Chr1:118761862-118981349 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression magna international louisville ky