Claudin-4 immunohistochemistry
WebApr 1, 2014 · Immunohistochemistry for claudin-4, a tight-junction-associated protein, has recently been shown to distinguish adenocarcinoma from malignant mesothelioma, mostly in surgical specimens. Our aim... WebClaudin-4 (Clostridium perfringens enterotoxin receptor) is a tight junction protein encoded by the gene CLDN4. Expression of Claudin-4 has been associated with either poor …
Claudin-4 immunohistochemistry
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WebProduct Details Target Information Plays a major role in tight junction specific obliteration of the intercellular space, through calcium independent cell adhesion activity. For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization. Bioinformatics Protein Aliases: Claudin-15 WebThe evaluation of claudins (CLDNs) expression pattern in tumours can be important to understand breast carcinogenesis. The study of CLDNs became more appealing since it was found that CLDN3 and CLDN4 are putative therapeutic targets for Clostridium perfrigens enterotoxin (CPE), as well as for monoclonal antibody-based therapy.
WebNov 17, 2024 · Immunohistochemistry (IHC) was performed on FFPE tissue using the following primary antibodies: claudin-1 (Abcam, ab56417, 1:250), claudin-2 (Abcam, … WebJun 29, 2024 · Detection of the expression of MD2 protein, tight junction protein (including occludin and claudin‐1) by IHC . Mouse intestinal tissue was fixed with 4% PFA, paraffin‐embedded and then sliced, baked at 60℃ for 2 h, treated with xylene and gradient alcohol. The slices were placed in 0.01 mol/L citrate buffer (PH = 6.0), heated at 98℃ in ...
WebClaudin-4 immunohistochemistry is a useful pan-carcinoma marker for serous effusion specimens. in Basaloid squamous cell carcinomas , SOX2 and PCNA had diffuse staining patterns in almost all cancer cells. SOX2 overexpression had little effect on the expression levels of claudin4, occludin and PCNA; WebComprehensive genomic and immune profiling for all solid tumors with one tissue sample View Specimen Requirements Learn More Labcorp® Plasma Focus™ A guideline-driven liquid biopsy test that targets 33 clinically actionable or relevant genes for advanced solid tumors Learn More IntelliGEN ® Myeloid
WebNov 7, 2012 · For all these cases, immunohistochemistry for estrogen and progesterone receptors, Ki-67, and Her2 had already been performed, whereas Her2 2+ cases had …
WebClaudin-4 immunohistochemistry was performed on cell-block paraffin sections and scored for staining intensity, staining pattern (cytoplasmic versus membranous), and percentage of positive tumor cells. Appropriate positive and negative controls were used throughout. RESULTS: All cases of mesothelioma were negative for claudin-4 (0 of 64). la chumbera granada spainWebJan 13, 2014 · Immunohistochemistry for claudin‐4, a tight‐junction‐associated protein, has recently been shown to distinguish adenocarcinoma from malignant mesothelioma, … jeansinn goesWebAnti-Claudin 4 antibody [EPRR17575] (ab210796) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast production Success from the first experiment – confirmed specificity through extensive validation lachung restaurantsWebClaudin-4 should be used as part of a panel of immunohistochemical stains to evaluate neoplasms of epithelial differentiation from benign mesothelial cells and mesothelial … lachung temperature in mayWebClaudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux. lachung temperature in juneWebImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 4 antibody [EPRR17575] (ab210796) Immunohistochemical analysis of paraffin-embedded … lachung prideWebImmunogen Synthetic peptide within Human Claudin 1 aa 150 to the C-terminus (C terminal). The exact sequence is proprietary. Database link: O95832 General notes This product is FOR RESEARCH USE ONLY. For commercial use, please contact [email protected]. lachung temperature in january